The potential health impacts of GLP-1 for weight loss.  Beyond standard gastrointestinal side effects, these medications can accelerate age-related muscle and bone density loss, and their delayed gastric emptying can interfere with the absorption of oral Hormone Replacement Therapy (HRT). Because side effects vary widely, it is important to work with a well informed care provider to manage dosage adjustments and/or discuss switching to non-oral HRT. To learn or and to request a consultation call (415) 548-7901 or feel free to use our online appointment form.